SAN DIEGO — Neuromodulation of the sphenopalatine ganglion (SPG) through transnasal evaporative cooling is a promising nonpharmacologic treatment for acute migraine, results of a randomized controlled trial suggested.
The SPG, a nerve bundle located behind the nasal passages, has been implicated in migraine pathophysiology.
Mi-Helper is an investigational, semi-portable device, similar in size to sleep apnea machine, that uses dry, room-temperature air to cool the nasal cavity, which calms the SPG, relieving migraine pain and the need for medication.