Using Only Air, Intranasal Device Treats Migraine Attacks

April 8, 2025

SAN DIEGO — An investigational device that delivered conditioned room air intranasally treated acute migraine attacks without drugs, a randomized sham-controlled study showed.

Compared with sham, transnasal dry air flow at 10 L per minute using the Mi-Helper device was effective in treating acute migraine, said MaryAnn Mays, MD, of the Cleveland Clinic, in a late-breaking presentation at the American Academy of Neurologyopens in a new tab or window (AAN) annual meeting.

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